Author/Editor     Vovk, I; Simonovska, B; Kompan, L; Prošek, M
Title     TCL determination of mannitol and lactulose on amino HPTLC plates
Type     članek
Source     In: Nyiredy S, editor. Planar chromatography 2003. Proceedings of the international symposium on planar separations; 2003 Jun 21-23; Budapest. Budapest: Research institute for medicinal plants,
Publication year     2003
Volume     str. 433-9
Language     eng
Abstract     Analytical method for the determination of lactulose and mannitol in urine samples on the same amino HPTLC plate was developed. The method enables the densitometric quantification of lactulose using fluorescence mode and mannitol using absorption mode after detection with AgNO3 reagent. The ratio of lactulose/mannitol excretion in urine after their administration is of great importance for evaluation of malabsorption and intestinal permeability disruption in some diseases.
Descriptors     LACTULOSE
MANNITOL
CHROMATOGRAPHY, HIGH PRESSURE LIQUID
CALIBRATION
INTESTINAL ABSORPTION
MULTIPLE ORGAN FAILURE