Avtor/Urednik | Peč, M; Adamicova, K; Chribikova, I; Jautova, J; Peč, J | |
Naslov | Regression of dermal mast cell infiltrates in patients with cutaneous mastocytosis | |
Tip | članek | |
Vir | Acta Dermatovenerol Alp Pannon Adriat | |
Vol. in št. | Letnik 12, št. 3 | |
Leto izdaje | 2003 | |
Obseg | str. 89-93 | |
Jezik | eng | |
Abstrakt | Background. Fourteen children with urticaria pigmentosa (UP) and two with disseminated cutaneous mastocytosis (DCM) were followed. Methods. Three skin biopsies were performed: the first one before the age of 2 years, the second one after 1-year treatment and the third 6 years after the second. Results. The repeated biopsy after the 1-year treatment resulted in a 20-60% regression of the mast cell infiltrates, while the third one disclosed a 70-90% reduction of these infiltrates. In UP patients the mast cell infiltrate changed from vessel unit type >55 micro m to <55 micro m. In both the DCM patients the mast cell infiltrate changed into the type >55 micro m. In the two nontreated UP patients the mast cell infiltrate type remained <55 micro m. Conclusion: The authors observed a spontaneous regression of the mast cell infiltrates in mastocytosis patients during adolescence; the treatment can however essentially influence their reduction. | |
Deskriptorji | URTICARIA PIGMENTOSA MAST CELLS CHILD BIOPSY |