Avtor/Urednik     Vlaisavljević, V; Reljič, M; Gavrić-Lovrec, V; Zazula, D; Sergent, N
Naslov     Measurement of perifollicular blood flow of the dominant preovulatory follicle using three-dimensional power Doppler
Tip     članek
Vir     Ultrasound Obstet Gynecol
Vol. in št.     Letnik 22
Leto izdaje     2003
Obseg     str. 520-6
Jezik     eng
Abstrakt     Objective To establish whether we might predict the outcome of unstimulated in-vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles with quantitative indices of peri follicular blood flow assessed with three-dimensional (3D) reconstruction of power Doppler images. Methods This prospective study included an analysis of 52 unstimulated cycles. Color and power Doppler ultrasound examinations of a single dominant preovulatory follicle were per formed on the day of oocyte pick-up. Witb 3D reconstruction and processing, quantitative indices were obtained i.e. the percentage of volume showing a flow signal (VFS) inside a 5-mm capsule of perifollicular tissue and the percentage of VFS of each of the tbree largest vessels in this capsule. These indices as well as pulsed Doppler indices were compared between the groups of cycles with different outcomes using a one-way ANOVA test. Results In nine cycles no oocyte was retrieved (Group A), in seven cycles no fertilization occurred (Group B) and in 30 cycles no implantation occurred (Group C). Six cycles resulted in pregnancy (Group D). There were no statistically significant differences in pulsed and power Doppler indices between these groups. However, the percentage of VFS in the capsule was higher than average in cycles with implantation (19.22 +- 16.82 vs. 12.42 +- 8.89, NS) and the percentage of VFS in the main vessel exhibited lower than average values in cycles with implantation (20.66 +- 10.05 vs. 39.84 +- 20.13), but only reached borderline statistical signi ficance (F = 2.457, P = 0.074). Conclusion It can be bypothesized that the follicles containing oocytes able to produce a pregnancy have a distinctive and more uniform perifollicular vascular network.
Deskriptorji     FERTILIZATION IN VITRO
SPERMATOZOA
OVARY
GRAAFIAN FOLLICLE
OOCYTES
ULTRASONOGRAPHY, DOPPLER, PULSED
ANALYSIS OF VARIANCE
PROSPECTIVE STUDIES