Author/Editor		Kansky, Andrej A; Poljak, Mario
Title		Pomen okužbe s humanimi virusi papiloma v etiopatogenezi epitelijskih novotvorb ustne votline
Translated title		Significance of human papilloma virus infection in the etiopathogenesis of oral epithelial malignancies
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 43, št. Suppl 3
Publication year		2004
Volume		str. 289-92
Language		slo
Abstract		HPV infection can etiologically contribute to the development of certain tumours in the oral cavity. However, understanding of the etiological role of HPV in oral carcinogenesis is hampered by the fact that there is a marked variation in the HPV-DNA prevalence rate in tissue specimens of oral and oropharyngeal squamous cell carcinomas (OSCC), varying from 0% to 100%. In our study,104 tissue specimens from Slovene patients were investigated and HPV DNA was detected in 9.6% of cases. These results are comparable to recently published articles found in the literature.
Summary		Okužba s humanimi virusi papiloma (HPV) je lahko vzrok za nastanek tumorskih sprememb v ustni votlini in ustnem delu žrela. V literaturi obstaja velika razlika v dokazanih prevalencah HPV-DNA (0-100%) pri ploščatoceličnem karcinomu ustne votline in ustnega dela žrela. V naši raziskavi, narejeni na tkivnih vzorcih 104 slovenskih bolnikov, smo dokazali 9,6% prekuženost, kar je primerljivo s podatki v literaturi.
Descriptors		MOUTH NEOPLASMS PAPILLOMAVIRUS, HUMAN OROPHARYNGEAL NEOPLASMS CARCINOMA, SQUAMOUS CELL IN SITU HYBRIDIZATION POLYMERASE CHAIN REACTION DNA, VIRAL