Author/Editor		Mikulandra, F; Periša, M; Merlak, I; Šikić, D; Jerković, J
Title		Novorođenče iz zakašnjele trudnoće
Translated title		Newborn infants of advancing pregnancy
Type		članek
Source		Arh Zašt Majke Djeteta
Vol. and No.		Letnik 35, št. 2
Publication year		1991
Volume		str. 93-9
Language		cro
Abstract		Of 23 915 newborn infants delivered from singleton pregnancies during the 1970-1989 period, 278 (1.16 per cent) were born to women who were 40 years of age or older at conception (late pregnancy). Controls were 14 400 primiparas and pluriparas (two to four deliveries). There were 54.0 per cent and 51.4 per cent (P more than 0.05) of male infants delivered in the late pregnancy and control group, respectively. Asphyxiated infants from the two groups were found in 12.6 per cent and 3.8 per cent of the cases (P less than 0.001), respectively. There was no difference in the incidence of low birthweight infants, large infants (more/equal 4000 g) and growth-retarded infants (490.05). Neonatal morbidity was two and half times higher in the late pregnancy group (P less than 0.001), whereas congenital anomalies were four and half times more frequent than in the control group (P less than 0.001). In the late pregnancy group there were 3.24 per cent of infants with congenital anomalies, whereas in the control group there were 0.07 per cent of such cases. There was one chromosome abnormality in 93 and 847 deliveries, and one infant with Down's syndrome in 93 and 1029 deliveries in the late pregnancy and control groups, respectively. Late fetal death was four times more frequent in the late pregnancy group, whereas there was no difference in early neonatal deaths (P more 0.05). The overall perinatal mortality rate in the late pregnancy group was two and a half times higher than in the control group (P less than 0.001). The authors conclude that newborn infants from late pregnancies are a high-risk group and require intensive neonatal care. Newborn infants of primiparous women are at especially high risk because of a great number of low birth-weight and growth-retarded infants
Descriptors		MATERNAL AGE 35 AND OVER PREGNANCY OUTCOME PARITY INFANT MORTALITY RISK FACTORS ABNORMALITIES INFANT, NEWBORN, DISEASES PREGNANCY INFANT, NEWBORN ADULT