Author/Editor		Gajzer, Borut; Koželj, Miran; Krebs, Bojan
Title		Kirurško zdravljenje bolnikov z rakom debelega črevesa na Oddelku za abdominalno in splošno kirurgijo Splošne bolnišnice Maribor v obdobju 1998-2001
Translated title		Surgical treatment of patients with colon cancer in Department for abdominal and general surgery at Maribor general hospital in years 1998-2001
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 73, št. 7-8
Publication year		2004
Volume		str. 589-92
Language		slo
Abstract		Background. The aim of this paper is to present and assess a surgical treatment of patients with colon cancer. Methods. All patients with colon cancer, who were operated in years 1998-2001, were included in the analysis. We have collected data including patients age, localization and stage of cancer, types of preformed procedures, postoperative mortality, disease recurrence and survival of the patients. Results. We have operated on 308 patients with histological evidence of colon cancer in above mentioned period. The average patients age was 665 years (SD = 11.1; 95% CI: 44.388.7). Primary tumor was most commonly (36%) located in sigmoidcolon. UICC stages were as follows: stage I 34patients, 11%; stage II 141, 46%; stage Ill 64, 21%; stage IV 69, 22%. We have performed 287 resections of colon (93% resectabillity), of these 214 (75%) were potentially curative R0 resections. Share of urgent procedures was 21%. In the postoperative period 22 patients (7%) have died. Postoperative mortality was significantly higher by urgent (19%) compared to scheduled procedures (4%) (chi2 = 16; df = 1; p = 0,005). In the observed time 22% of patients developed recurrent cancer Mean survival rate of ourpatients was 1274 days or 3.5years (SD = 191; 95% CI: 900-1648). Calculated overall five years survival rate was 45%. Conclusions. Planned and registered surgical treatment of patients with colon cancer, surgical specialization in colon surgery and adjuvant oncological treatment have shown the same incentive results, reflected in increased survival rate.
Summary		Izhodišča. Namen pričujočega dela je prikazati in ovrednotiti kirurško zdravljenje bolnikov z rakom debelega črevesa. Metode. V analizo smo vključili vse bolnike z rakom debelega črevesa (RDČ), operirane v letih 1998-2001. Zbrali smo podatke o starosti bolnikov, umestitvi in stadiju rakov, vrstah operacij, pooperativni smrtnosti, ponovitvah bolezni in preživetju teh bolnikov. Rezultati. V omenjenem obdobju smo operirali 308 bolnikov s histološko dokazanim rakom debelega črevesa. Povprečna starost bolnikov je bila 66,5 leta (SD = 11,1; 95% IZ: 44,3-88,7). Primarni tumor je bil največkrat (36%) v sigmoidnem delu kolona. Razporeditev po klasifikaciji UICC je bila: stadij I 34 bolnikov, 11%; stadij II 141, 46%; stadij III 64,21%; stadij IV 69, 22%. Naredili smo 287 resekcij debelega črevesa (93-odstotna resektabilnost), od tega 214 (75%) potencialno ozdravjenih resekcij RO. Delež urgentnih operacij je bil 21%. V pooperativnem obdobju je umrlo 22 bolnikov (7%). Pooperativna smrtnost je bila statistično značilno višja pri urgentnih posegih (19%) v primerjavi s programsko operiranimi bolniki (4%) (hi2 = 16; df = 1; p = 0,005). V opazovanem času po posegu je pri 22% bolnikov prišlo do ponovitve bolezni. Srednje preživetje naših bolnikov je 1274 dni ali 3,5 leta (SD = 191; 95% IZ: 900-1648). Izračunano celokupno petletno preživetje znaša 45%. Zaključki. Dobro zastavljeno in protokolirano zdravljenje bolnikov z RDČ, usmerjanje kirurgov v ožje področje kolorektalne kirurgije in adjuvantno onkološko zdravljenje dajejo spodbudne rezultate, ki se zrcalijo v boljšem preživetju bolnikov.
Descriptors		COLONIC NEOPLASMS NEOPLASM STAGING SURVIVAL RATE