| Author/Editor | Bilban, Milan | |
| Title | Mutagenetsko testiranje učencev osnovne šole | |
| Translated title | Chromosome aberrations study of pupils in high radon level elementary school | |
| Type | članek | |
| Source | Sanitas et labor | |
| Vol. and No. | Letnik 3, št. 1 | |
| Publication year | 2004 | |
| Volume | str. 99-118 | |
| Language | slo | |
| Abstract | A number of studies imply that the exposure to radon can cause lung cancer. In our environment radon can be found in lithosphere only, from where it is released as a gas into the atmosphere. The Karst region with its open landscape is a special problem, since its geologic features prevent the stopping of radon being released into the air. Older buildings have been built in times when the awareness of the harmful effect of radon was not so widespread. This has resulted in many mistakes during construction thus allowing the penetration of radon. One of such buildings is the analysed school S3, where the measurements of radon content and its decay products have been carried out. Some mutagene tests have also been carried out, indicating a statistically significant increased share of structural chromosomal aberrations and micronucleus, compared to the control group. Of course, the effects of their living environment and other genotoxic influence can not be excluded After the implementation of some technical measures (new foundations, ventilation), the concentration of radon and its decay products decreased significantly; as far as other measures are concerned, future monitoring and in cases of particularly significant deviations individual genetic counselling are suggested. | |
| Summary | Številne raziskave nakazujejo na to, da izpostavljenost radonu lahko povzroča raka na pljučih. V življenjskem okojju najdemo radon samo v zemeljski skorji, od koder potem kot plin izhaja v atmosfero. Poseben problem predstavlja Kras s svojo odprtostjo terena, ki s svojimi geološkirni značilnostmi onemogoča zaustavitev prehajanja radona v zrak. Starejše stavbe so bile zgrajene v času, ko se ljudje še niso zavedali nevarnih vplivov radona, zato so izvedli mnogo napak v gradnji, ki so omogočale prehod radona. Ena od takih stavb je bila tudi analizirana osnovna šola S3, kjer so bile opravljene meritve koncentracije radona in njegovih potomcev. Opravljeni so bili tudi mutagenetski testi učencev in učiteljev, ki nakazujejo statistično signifikantno večji delež strukturnih kromosomskih aberacij in mikronukleusov v primerjavi s kontrolno skupino. Seveda pa pri tem ne moremo izključiti tudi vpliva njihovega bivalnega okolja in tudi drugih genotoksičnih vplivov. Po opravljenih tehničnih ukrepih (nova temeljna plošča, prezračevanje) se je koncentracija radona in njegovih potomcev pomembno zmanjšala, od ostalih ukrepov pa svetujemo še nadaljnji monitoring ter v primerih posebno visokih odstopanj individualno genetsko svetovanje. | |
| Descriptors | RADON RADON DAUGHTERS AIR POLLUTANTS, RADIOACTIVE RADIATION DOSAGE RADIOMETRY CHILD MUTAGENICITY TESTS CHROMOSOME ABERRATIONS MICRONUCLEUS TESTS SCINTILLATION COUNTING BLOOD CELL COUNT HEMOGLOBINS SCHOOLS |