Author/Editor		Lopuh, Mateja
Title		Vpliv torakalne epiduralne analgezije na dihalno funkcijo po pljučnih operacijah: primerjava ropivakaina z mešanico bupivakaina, morfina in klonidina
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		2004
Volume		str. 67
Language		slo
Abstract		Introduction Analgesic efficacy of 0.2% ropivacaine for pain treatment after lung surgery has been evaluated, using patient controlled epidural analgesia (PCEA). Lung function after surgery has been assessed by spirometric measurements of forced expiratory volume in first second (FEV,) and forced vital capacity (FVC) and measurements of maximal inspiratory (MIP) and expiratory pressures (MEP) and results were compared between the two groups of patients, receiving 0.2% ropivacaine and a mixture of bupivacaine, morphine and clonidine. Side effects of morphine and piritramide were compared between groups. Methods 37 patients, ASA II and III with lung cancer, undergoing lobectomy, were included in a prospective, randomized, double blind study after obtaining their written informed consent. On a day before the planned surgery, the patients performed baseline measurements of FEV,, FVC, MlP and MEP. Patients were randomly assigned to two groups. In group A 0.2% ropivacaine in 100 ml of saline was used for postoperative pain treatment by PCEA and in group 8 a mixture of 10 mg morphine, 50 mg bupivacaine in 0.15 mg clonidine in 100 ml of saline. Epidural cathefer was inserted at the T6-7 or T7-8 level and its position was confirmed by 4 ml of 2% lidocaine. After that a preemptive dose of 4 mg morphine was injected through the catheter. Both groups of patients underwent surgery under same general anaesthesia. (Abstract truncated at 2000 characters)
Descriptors		PAIN, POSTOPERATIVE ANALGESIA, EPIDURAL BUPIVACAINE CLONIDINE MORPHINE SPIROMETRY FORCED EXPIRATORY VOLUME VITAL CAPACITY LUNG NEOPLASMS OXIMETRY BLOOD PRESSURE CENTRAL VENOUS PRESSURE PAIN MEASUREMENT