Author/Editor		Mesec, A
Title		Parkinsonova bolezen
Translated title		Parkinson's disease
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 31, št. 1
Publication year		1992
Volume		str. 65-76
Language		slo
Abstract		In the last few decades, remarkable progress has been made in the management of Parkinson's disease, based mainly on recent discoveries in the fields of pathophysiology and biochemistry. The author briefly outlines biochemical changes occuring in the dopaminergic system in Parkinson's disease, and describes clinical manifestations of this disease. He stresses the importance of clinical diagnosis and presents errors most commonly made in differential diagnosis. Today, a combined use of levodopa, dopamine agonists and selective MAO inhibitors seems to be the optimal therapy yet the problem of adverse effects of long-term levodopa administration still remains to be solved. The author acquaints us with the attempts hitherto made to reduce and eliminate these effects. He emphasizes individuai approach to the patient and presents therapeutic measures taken to relieve specific symptoms of patients with Parkinson's disease.
Descriptors		PARKINSON DISEASE DIAGNOSIS, DIFFERENTIAL DOPAMINE DOPAMINERGIC AGENTS LEVODOPA ANTIPARKINSON AGENTS