Avtor/Urednik		Štefanič-Anderluh, Petra; Anderluh, Marko; Ilaš, Janez; Mravljak, Janez; Sollner-Dolenc, Marija; Stegnar, Mojca; Kikelj, Danijel
Naslov		Toward a novel class of antithrombotic compounds with dual function. Discovery of 1,4-bentoxazin-3(4H)- one derivates possessing thrombin inhibitory and fibrinogen receptor antagonistic activities
Tip		članek
Vir		J Med Chem
Vol. in št.		Letnik 48
Leto izdaje		2005
Obseg		str. 3110-3
Jezik		eng
Abstrakt		A novel class of potential antithrombotic compounds with moderate thrombin inhibitory and fibrinogen receptor antagonistic activity ia described. Combination of anticoagulant and antiaggregatory activity in the same molecular entity is presented as a new promising approach in the search for novel antithrombotic agents.
Deskriptorji		THROMBOEMBOLISM FIBRINOLYTIC AGENTS THROMBIN PLATELET AGGREGATION INHIBITORS BINDING SITES DRUG APPROVAL