Author/Editor		Grmec, Štefek; Mally, Štefan; Klemen, Petra
Title		Glasgow coma scale score and QTc interval in the prognosis of organophosphate poisoning
Type		članek
Source		Acad Emerg Med
Vol. and No.		Letnik 11, št. 9
Publication year		2004
Volume		str. 925-30
Language		eng
Abstract		Objectives: The aim of this study was to assess the applicability of the Glasgow Coma Scale (GCS) score and the Q-T interval corrected for heart rate (QTc interval) in predicting outcome and complications in patients with organophosphate (OP) poisoning. Methods: This prospective, observational study included 65 patients older than 18 years. In the out-of-hospital setting, the end-tidal carbon dioxide (ETCOz), oxygen saturation (SaOz), QTc interval, and GCS score were monitored in each patient. A statistical comparison was then made between the group with respiratory failure and the group without this complication. Results: The group with complications had significantly different values of measured parameters-a longer QTc interval and a lower GCS score, a higher number of intubations, and worse outcomes (p<0.05). The two measures, GCS score and QTc interval, have been shown to be equally good in predicting respiratory failure and hospital mortality in patients with OP poisoning. Conclusions: In the initial out-hospital care of patients with OP poisoning, it is essential to monitor QTc interval and GCS score. These measures help with prognosis, and may suggest when to initiate precautions to prevent complications (i.e., respiratory failure). The simplicity and promptness of these methods allow providers to perform early and effective triage.
Descriptors		RESPIRATORY INSUFFICIENCY GLASGOW COMA SCALE PHOSPHORIC ACID ESTERS APACHE CHOLINESTERASES SEX FACTORS MIDDLE AGE PROGNOSIS PROSPECTIVE STUDIES ROC CURVE SENSITIVITY AND SPECIFICITY