Author/Editor		Vrtovec, Bojan
Title		Levosimendan - nov pristop k zdravljenju akutnega popuščanja srca
Translated title		Levosimendan - a novel approach to acute heart failure management
Type		članek
Source		In: Bručan A, Gričar M, Vajd R, editors. Urgentna medicina: izbrana poglavja. Zbornik 12. mednarodni simpozij o urgentni medicini; 2005 jun 15-18; Portorož. Ljubljana: Slovensko združenje za urgentno medicino,
Publication year		2005
Volume		str. 38-9
Language		slo
Abstract		Levosimendan is a calcium-sensitizing drug that stabilizes the troponin C molecule in cardiac muscle, thus prolonging its effects on contractile proteins. Thereby it effectively improves cardiac hemodynamics, which results in increased cardiac output and decreased pulmonary wedge pressure. The results of clinical studies have demonstrated that Levosimendan therapy is not associated with heart rhythm disturbances and that it effectively improves the outcome of patients with acute heart failure. Therefore, Lemosimendan appears to represent an important new treatment for acute heart failure, and as such it is being increasingly used also in Slovenia.
Descriptors		HEART FAILURE, CONGESTIVE TROPONIN C