Author/Editor     Zorn, B
Title     Marqueurs biochimiques du sperme a la recherche de l'inflammation genitale: interet de la determination de l'elastase
Translated title     Sperm biochemical markers of genital tract inflammation: usefulness of elastase determination
Type     članek
Source     Gynecol Obstet Fertil
Vol. and No.     Letnik 33, št. 9
Publication year     2005
Volume     str. 678-83
Language     fre
Abstract     Genital tract inflammation was for a long time suspected of inducing sterility in the male. The role of leukocytes in sperm changes is still debated. The identification of inflammation is based on the presence of activated leukocytes and the elastase measurement. Residual inflammation is evaluated by the reactive oxygen species activity. The true damage caused by inflammation on spermatozoa is reflected in negative changes observed during sperm apoptosis. Increased sperm DNA fragmentation is frequently observed while classical sperm characteristics are not modified automatically. The diagnosis of genital tract inflammation, follow-up after treatment and prognosis in terms of fertility require the use of different and complementary parameters.
Descriptors     GENITAL DISEASES, MALE
INFLAMMATION
BIOLOGICAL MARKERS
SPERMATOZOA
INFERTILITY, MALE
PROGNOSIS
DNA FRAGMENTATION
INFECTION
LEUKOCYTES
PANCREATOPEPTIDASE