Author/Editor		Štrumbelj, Iztok; Ribič, Helena; Franko-Kancler, Tatjana; Božanić, Vinko; Dermota, Urška; Sarjanović, Ljudmila; Kavčič, Martina; Harlander, Tatjana; Naveržnik-Troha, Breda; Seme, Katja
Title		Proučevanje odpornosti proti eritromicinu pri izolatih bakterije Streptococcus pyogenes iz dihal bolnikov v Sloveniji
Translated title		Study od erythromycin resistance in Streptococcus pyogenes isolates from respiratory tract specimens of patients in Slovenia
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 45, št. Suppl 2
Publication year		2006
Volume		str. 23-8
Language		slo
Abstract		Objective: To determine the rates of erythromycin resisiance in Streptococcus pyogenes isolates obtained from respiratory tract specimens in Slovenia during thc period 2007-2004. Methods: In 2001-2004, eight Slovene microbiology laboratories isolated 3919 S. pyogenes isolates from respiratory tract specimens. Their susceptibility to erythromycin was determined. The data were analyzed with regard to patient age, geographic region and other factors. Results: The overall rate of resistance to erythromycin in all tested strains was 8.4%. Resistance was more common in adults than in children. There were great differences among individual regions; the highest rate of resistance was found in the Koper region (22.8%) and the lowest in the Nova Gorica region (5.3%). The rate of resistance increased from 5.6% in 2001 to 11.9% in 2004. Conclusions: The observed increase in erythromycin resistance and current rates of resistance are a cause of concern. Efficient interventions to prevent antibiotic resistance are necessary.
Summary		Namen: Na izolatih, pridobljenih iz dihal v Sloveniji v letih od 2001 do 2004, prikazati podatke o odpornosti bakterijske vrste Streptococcus pyogenes proti eritromicinu. Metode: V osmih slovenskih mikrobioloških laboratorijih so v letih od 2001 do 2004 iz dihal osamili 3919 izolatov vrste Streptococcus pyogenes in pri njih določili občutljivost za eritromicin. Podatke so analizirali glede na starost bolnikov, regionalni izvor izolatov in druge dejavnike. Rezultati: Delež odpornosti proti eritromicinu v celotnem obdobju je bil 8,4%. Odpornost je bila pogostejša pri odraslih kot pri otrocih. Razlike med regijami so bile velike, največji delež odpornih izolatov so ugotovili v koprski regiji (22,8 %), najmanjšega v goriški regiji (5,3 %). Odstotek odpornosti se je povečal s 5,6 % v letu 2001 na 11,9 % v letu 2004. Zaključek: Ugotovljeni deleži odpornih izolatov proti eritromicinu in trend naraščanja odpornosti so razlog za zaskrbljenost. Potrebni so učinkoviti ukrepi za preprečevanje odpornosti.
Descriptors		RESPIRATORY TRACT INFECTIONS STREPTOCOCCUS PYOGENES ERYTHROMYCIN ESTOLATE