| Abstract | | A normal immune response in children, especially in newborns, is dependent on a number of factors: strong physical barriers, developed immune mechanisms, T-cell subpopulations that effect suppression and bacterial flora, which stimulate the immune response. In the newborn, several of these pathways are still not developed, allowing for unwanted infection or sensitization. With age, the immune system matures, and in most individuals this allows for normal defence against infections. Immunological techniques are usually used to detect, identify, and quantitate immune function and inflammatory mediators in order to detect any deficient immune response and/or inflammatory consequences of immune disorders. Following immune functions may provide a deeper insight into physiological homeostasis as well as better detection of immune-mediated diseases.
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