Avtor/Urednik		Kšela, Urša; Zemljič, Eva; Rakuša, Martin; Čokolič, Miro
Naslov		Glycemic control before and after starting insulin therapy in obese and other type 2 diabetics
Tip		članek
Vir		Diabetol Croat
Vol. in št.		Letnik 35, št. 3
Leto izdaje		2007
Obseg		str. 59-62
Jezik		eng
Abstrakt		Type 2 diabetes mellitus is a chronic progressive disease slowly reaching a pandemic extent. Its prevalence is growing in the younger population, probably due to the epidemic of obesity. Numerous clinical and randomized studies have shown that morbidity and mortality due to chronic complications are decreased significantly by good glycemic control. The aim of our study was to assess the glycemic control in patients prior to starting insulin therapy and to establish the extent to which glycated hemoglobin (HbA [below] 1c) level decreased upon the introduction of therapy in patients grouped according to their body mass index. According to the American Diabetes Association (ADA) and International Diabetic Federation (IDD) guidelines, HbA [below] 1c was too high prior to insulin therapy. All patients, i. e. those with normal body weight and overweight, benefited from insulin therapy. The introduction of insulin therapy resulted in a statistically significant decrease in HbA [below] 1c level and less new microvascular complications. A more rapid recruiting of patients for insulin therapy would significantly decrease the respective morbidity and mortality rates, and serve to approach glycemic control in accordance with ADA and IDF guidelines.
Deskriptorji		OBESITY INSULIN INSULIN BODY WEIGHT