Author/Editor		Samec, T; Jan, J
Title		Klorheksidin v endodontiji
Translated title		Chlorhexidine in endodontics
Type		članek
Source		Zobozdrav Vestn
Vol. and No.		Letnik 62, št. 2-3
Publication year		2007
Volume		str. 85-8
Language		slo
Abstract		Chlorhexidine is one of the most widely used antiseptics in medicine. It is a symmetrical molecule composed of two chlorophenyl rings and two biguanide groups connected by a hexamethylene chain. Chlorhexidine changes the permeability of bacterial membrane, causing loss of intracellular content and in higher concentrations also coagulation of cytoplasm. In endodontics it is used as an irrigant or root canal medicament at concentrations of 0.2 to 2 per cent in the form of gel or solution. Excellent activity against Gram-positive microbes, fungal growth prevention, long lasting antimicrobial action within the root canal, and lower toxicity in comparison with sodium hypochlorite are attributes which make chlorhexidine a suitable agent for endodontic use. The article presents the antimicrobial properties and spectrum of chlorhexidine, its advantages and disadvantages in comparison with other root canal irrigants and calcium hydroxide, compatibility/incompatibility with other medicaments, indications for use and methods of application.
Descriptors		ROOT CANAL IRRIGANTS CHLORHEXIDINE