Avtor/Urednik		Beck, Halfdan; Dobritzsch, Doreen; Piškur, Jure
Naslov		Saccharomyces kluyveri as a model organism to study pyrimidine degradation
Tip		članek
Vir		FEMS Yeast Res
Vol. in št.		Letnik 8, št. 8
Leto izdaje		2008
Obseg		str. 1209-13
Jezik		eng
Abstrakt		The yeast Saccharomyces kluyveri (Lachancea kluyveri), a far relative of Saccharomyces cerevisiae, is not a widely studied organism in the laboratory. However, significant contributions to the understanding of nucleic acid precursors degradation in eukaryotes have been made using this model organism. Here we review eukaryotic pyrimidine degradation with emphasis on the contributions made with S. kluyveri and how this increases our understanding of human disease. Additionally, we discuss the possibilities and limitations of this nonconventional yeast as a laboratory organism.
Deskriptorji		AMIDOHYDROLASES ANIMALS EUKARYOTIC CELLS FUNGAL PROTEINS NUCLEIC ACID PRECURSORS PYRIMIDINES SACCHAROMYCES