| Author/Editor | Leskovšek, V; Pečar, S | |
| Title | Ključni encimi deoksiribonukleinske kisline kot mesto delovanja učinkovin | |
| Translated title | Some important DNA enzymes as drug target | |
| Type | članek | |
| Source | Farm Vestn | |
| Vol. and No. | Letnik 44, št. 3 | |
| Publication year | 1993 | |
| Volume | str. 103-18 | |
| Language | slo | |
| Abstract | In this review some important DNA enzymes and drugs, affecting on them have been presented. DNA polymerases, DNA methyltransferases and DNA topoisomerases are target of many antimicrobial and antitumor drugs. So the quinolones, as chemotherapeutics, are inhibitors of a group of bacterial DNA topoisomerases - DNA gyrases. The substances, which are also important for further development of antibacterial drugs, have been described. | |
| Descriptors | DNA POLYMERASES DNA MODIFICATION METHYLASES DNA TOPOISOMERASE DNA TOPOISOMERASE (ATP-HYDROLYSING) ANTINEOPLASTIC AGENTS ACYCLOVIR ENZYME INHIBITORS |