Author/Editor | Tomič, Viktorija; Uršič, Viktor | |
Title | Typing of Pseudomonas aeruginosa in cystic fibrosis patients: comparison of genotype and antimicrobial susceptibility | |
Translated title | Tipizacija Pseudomonas aeruginosa pri bolnikih s cistično fibrozo: primerjava genotipa in občutljivost za protimikrobna zdravila | |
Type | članek | |
Source | Zdrav Vestn | |
Vol. and No. | Letnik 79, št. 9 | |
Publication year | 2010 | |
Volume | str. 623-7 | |
Language | eng | |
Abstract | Background: The aim of our study was to determine the genotypes and antimicrobial susceptibility profiles of Pseudomonas aeruginosa isolates of cystic fibrosis (CF) patients. Methods: We included 18 P. aeruginosa isolates from 10 patients treated as in-patients or outpatients at University Clinic of Respiratory and Allergic Diseases Golnik between 1 January 2006 and 31 December 2008. Results: We determined 8 pulsotypes of P. aeruginosa. Pulsotypes A and C had 4 subtypes each. Different antimicrobial susceptibility patterns were observed in isolates with closely related macrorestriction profiles. Conclusions: We conclude that at a given time, patients with CF attending our clinic were colonized or infected with phenotypically and genotypically distinct strains of P. aeruginosa. | |
Descriptors | CYSTIC FIBROSIS PSEUDOMONAS AERUGINOSA GENOTYPE PHENOTYPE MICROBIAL SENSITIVITY TESTS ANTIBIOTICS |