Author/Editor     Tomič, Viktorija; Uršič, Viktor
Title     Typing of Pseudomonas aeruginosa in cystic fibrosis patients: comparison of genotype and antimicrobial susceptibility
Translated title     Tipizacija Pseudomonas aeruginosa pri bolnikih s cistično fibrozo: primerjava genotipa in občutljivost za protimikrobna zdravila
Type     članek
Source     Zdrav Vestn
Vol. and No.     Letnik 79, št. 9
Publication year     2010
Volume     str. 623-7
Language     eng
Abstract     Background: The aim of our study was to determine the genotypes and antimicrobial susceptibility profiles of Pseudomonas aeruginosa isolates of cystic fibrosis (CF) patients. Methods: We included 18 P. aeruginosa isolates from 10 patients treated as in-patients or outpatients at University Clinic of Respiratory and Allergic Diseases Golnik between 1 January 2006 and 31 December 2008. Results: We determined 8 pulsotypes of P. aeruginosa. Pulsotypes A and C had 4 subtypes each. Different antimicrobial susceptibility patterns were observed in isolates with closely related macrorestriction profiles. Conclusions: We conclude that at a given time, patients with CF attending our clinic were colonized or infected with phenotypically and genotypically distinct strains of P. aeruginosa.
Descriptors     CYSTIC FIBROSIS
PSEUDOMONAS AERUGINOSA
GENOTYPE
PHENOTYPE
MICROBIAL SENSITIVITY TESTS
ANTIBIOTICS