Avtor/Urednik		Popovič, Petar; Štabuc, Borut; Skok, Pavel; Šurlan, Miloš
Naslov		Transjugular intrahepatic portosystemic shunt versus endoscopic sclerotherapy in the elective treatment of recurrent variceal bleeding
Tip		članek
Vir		J Int Med Res
Vol. in št.		Letnik 38, št. 3
Leto izdaje		2010
Obseg		str. 1121-33
Jezik		eng
Abstrakt		The present study was designed to compare elective transjugular intrahepatic portosystemic shunts (TIPS) and endoscopic sclerotherapy (EST) in terms of their efficacy in preventing recurrent bleeding from gastro-oesophageal varices in patients with advanced liver cirrhosis and portal hypertension. Of 96 patients with at least three gastro-oesophageal variceal rebleeds, 50 were treated with elective TIPS and 46 with EST. Recurrent variceal bleeding was significantly more frequent in patients receiving EST treatment compared with those receiving TIPS (45.7% versus 6.3%, respectively). Cumulative 1- and 4-year survival in the TIPS group was 83.0% and 73.5%, respectively, compared with 69.8% and 39.8% in the EST group, respectively. The rate of portosystemic encephalopathy was 33.3% in the TIPS group and 37.0% in the EST group. Elective TIPS was more effective than EST in the prevention of gastro-oesophageal variceal rebleeding in cirrhotic patients, it improved survival and it was associated with a similar rate of portosystemic encephalopathy.
Deskriptorji		VARICOSE VEINS HEMORRHAGE HYPERTENSION, PORTAL SCLEROTHERAPY PORTASYSTEMIC SHUNT, TRANSJUGULAR INTRAHEPATIC ENDOSCOPY LIVER CIRRHOSIS