Author/Editor		Hodolič, Marina
Title		Rople of 18F-choline PET/CT in evaluation of patients with prostate carcinoma
Translated title		Preiskava 18F-choline PET/CT pri bolnikih z rakom prostate
Type		članek
Source		Radiol Oncol
Vol. and No.		Letnik 45, št. 1
Publication year		2011
Volume		str. 17-21
Language		eng
Abstract		Background. Choline presents a high affinity for maligna nt prostate tissue. It can be labelled with positron emitting 18f,and used for the evaluation of patients with prostate carcinoma by PET/CTimaging. The aim of this paper is to summarise our experience with fluoromethylcholine ('8f-choline) PET/CTin patients with prosta te cancer. Methods. In 4 months we investigated the patients with histopathological (or cytological) confirmed prosta te cancer. Two observers evaluated the early and late 18f-choline PETimages in correlation with corresponding localising CT images and using the semiquantitative standard uptake value (SUV)calculation. Results. The 18f-choline PET/CT was made in 50 patients with prosta te cancer. There were 18 patients after radical prostatectomy and 32 without surgery.ln allpatients wiff1but surgery the pathological uptake was seen in the prostate. ln 14 (44 %) patients of this group there was evidence of metastatic spread in local or distant Iymph nodes and/or bones. In out of 18 patients after radical prostatectomy the local recurrence was detected in 6 patients (33%) and distant metastases were present in 2 patients (10%). Conclusions. 18f-choline PET/CTseems to be useful imaging modality in patients with prosta te carcinoma; it can demonstrate spread of the disease preoperatively and detect the local recurrence after radical prostatectomy.
Descriptors		PROSTATIC NEOPLASMS TOMOGRAPHY, X-RAY COMPUTED TOMOGRAPHY, EMISSION-COMPUTED CHOLINE FLUORINE RADIOISOTOPES NEOPLASM STAGING FOLLOW-UP STUDIES