Author/Editor		Cerar, Andraž; Rakovec, Peter; Bunc, Matjaž
Title		Inappropriate sinus tachycardia treatment with ivabradine - three case reports
Translated title		Zdravljenje neustrezne sinusne tahikardije z ivrabradinom - predstavitev treh primerov
Type		članek
Source		Slov Kardiol
Vol. and No.		Letnik 8, št. 1-2
Publication year		2011
Volume		str. 49-51
Language		eng
Abstract		The inappropriate sinus tachycardia is a rare disease, characterized by heart rates 100 bpm or more during daytime and/or a mean heart rate of 90 bpm or more during holter monitoring. Mostly it is treated with a beta-blocker or verapamil and - if this therapy fails -transcatheter sinus node modulation is considered. For the last few years a new drug, a selective and specific If current blocker, ivabradine, has been available. We report the results of ivabradine therapy in three cases. In all of them ivabradine 5 mg bid successfully decreased the mean heart rate, measured by holter monitoring. Ivabradine therapy did not affect the exercise capacity in presented patients; however, in one patient, in whom combined therapy with bisoprolol was tested, the exercise test revealed a significant reduction in exercise capacity. Ivabradine seems to be an effective alternative for the inappropriate sinus tachycardia therapy.
Descriptors		TACHYCARDIA, SINUS ELECTROCARDIOGRAPHY, AMBULATORY EXERCISE TEST ION CHANNELS ADULT