Author/Editor		Song, JE; Krunic, AL
Title		A rare variant of generalized granuloma annulare presenting with chronic Epstein-Barr virus infection: coincidence or association?
Type		članek
Source		Acta Dermatovenerol Alp Pannon Adriat
Vol. and No.		Letnik 20, št. 4
Publication year		2011
Volume		str. 207-11
Language		eng
Abstract		We report a rare variant of generalized granuloma annulare (GGA) in a 62-year-old male patient. The patient presented with large, annular, violaceous patches on the upper arms and thighs. Histological findings were consistent with interstitial granuloma annulare. In addition, high titers of Epstein-Barr Viral Capsid Antigen (EBV VCA) and EBV Nuclear Antigen (EBVNA) antibodies were found. In-situ hybridization did not reveal EBV RNA in the skin lesions. Immune dysregulation in the setting of chronic EBV infection has been suggested as a contributing factor to the development of this rare variant of GGA.
Descriptors		GRANULOMA ANNULARE HERPESVIRUS 4, HUMAN EPSTEIN-BARR VIRUS NUCLEAR ANTIGENS IN SITU HYBRIDIZATION MIDDLE AGE IGG IGM