Avtor/Urednik		Watanabe, Kohei; Gazzoni, Marco; Holobar, Aleš; Miyamoto, Toshiaki; Fukuda, Kazuhito; Merletti, Roberto; Moritani, Toshio
Naslov		Motor unit firing pattern of vastus lateralis muscle in type 2 diabetes mellitus patients
Tip		članek
Vol. in št.		Letnik 48
Leto izdaje		2013
Obseg		str. 806-813
ISSN		0148-639X - Muscle & nerve
Jezik		eng
Abstrakt		Introduction We investigated the motor unit (MU) firing pattern in type 2 diabetes mellitus (T2DM) patients by means of multi-channel surface electromyography (SEMG). Methods Eight T2DM patients and 8 age-matched healthymen performed a ramp-up contraction up to 20% of maximal voluntary contraction (MVC). They also performed a sustained contraction at 10% of MVC during isometric knee extension. Multi-channel SEMG signals recorded from the vastus lateralis muscle were decomposed with the Convolution Kernel Compensation technique to extract individual MU firing patterns. Results During the ramp contraction, the extent of MU firing modulation was significantly attenuated in T2DM. Variability of MU firing rate was significantly higher in T2DM at later periods during the sustained contraction. Discussion Our findings suggest that T2DM patients manifest characteristic MU activity patterns due possibly to some degree of neuromuscular impairment affecting the integrity of MU firing modulation
Proste vsebinske oznake		type 2 diabetes mellitus multichannel surface electromyography knee extensors vastus lateralis firing rate