Avtor/Urednik     Čurin-Šerbec, V; Novak, D; Babnik, J; Turk, D; Gubenšek, F
Naslov     Immunological studies of the toxic site in ammodytoxin A
Tip     članek
Vir     FEBS Lett
Vol. in št.     Letnik 280, št. 1
Leto izdaje     1991
Obseg     str. 175-8
Jezik     eng
Abstrakt     Two monoclonal antibodies against the native ammodytoxin A and four site-directed polyclonal antibodies against synthetic peptides derived from the primary structure of the toxin were prepared in order to estimate the localization of its toxic site. Some of the antibodies neutralized the lethal toxicity of the toxin, thus indicating an approximate position of the toxic or receptor binding site on the molecule that is different from those predicted by comparison with a number of known sequences.
Deskriptorji     VIPER VENOMS
PHOSPHOLIPASES A
AMINO ACID SEQUENCE
ANTIBODIES, MONOCLONAL
ANTIGENS
BINDING SITES
CYTOTOXICITY TESTS, IMMUNOLOGIC
MICE
MICE, INBRED BALB C
MOLECULAR SEQUENCE DATA
PHOSPHOLIPASES A
PROTEIN CONFORMATION
STEREOISOMERS
VIPER VENOMS