Avtor/Urednik		Favaro, L; Caplin, JL; Fettich, JJ; Dymond, DS
Naslov		Sex differences in exercise induced left ventricular dysfunction in patients with syndrome X
Tip		članek
Vir		Br Heart J
Vol. in št.		Letnik 57, št. 3
Leto izdaje		1987
Obseg		str. 232-6
Jezik		eng
Abstrakt		Clinical, electrocardiographic, and scintigraphic data were reviewed from 32 patients (18 men and 14 women) who had syndrome X (chest pain, evidence of ischaemia, and normal coronary arteries without coronary vasospasm). The mean (SD) resting left ventricular ejection fraction, determined by first pass radionuclide angiography was 62.6 (9.2) percent and was greater than 50 percent in all subjects. There was no significant difference between men and women. On exercise, left ventricular ejection fraction decreased significantly to 57.4 (13.0) percent. In 17 of 32 subjects there was a fall in left ventricular ejection fraction of greater than 5 percent, and regional wall motion abnormalities developed in 12 subjects. The fall in left ventricular ejection fraction on exercise was significant in women (from 61.9 (8.5) percent at rest to 54.0 (9.8) percent on exercise) but not in men (from 63.2 (9.8) percent at rest to 60.0 (14.8) percent on exercise). Exercise left ventricular ejection fraction fell by greater than 5 percent in 10 (71 percent) of 14 women and in seven (39 percent) of 18 men. Dyskinetic segments developed in eight (57 percent) of 14 women and only four (22 percent) of men. Exercise duration in women was significantly shorter than in men (4.1 (1.5) vs 6.6 (2.1) minutes) and was the only one of several clinical and scintigraphic variables that correlated with the change in left ventricular ejection fraction on exercise. In this selected group of subjects with chest pain and angiographically normal coronary arteries, exercise induced left ventricular dysfunction, as shown by a fall in ejection fraction or the development of regional abnormalities, is a common finding.(ABSTRACT TRUNCATED AT 250 WORDS)
Deskriptorji		CORONARY DISEASE EXERTION HEART ADULT ANGINA PECTORIS CORONARY DISEASE CORONARY VESSELS HEART VENTRICLE MIDDLE AGE SEX FACTORS STROKE VOLUME SYNDROME