Avtor/Urednik		Lučovnik, Miha; Tul, Nataša; Verdenik, Ivan; Blickstein, Isaac
Naslov		Perinatal outcomes in singleton and twin pregnancies following first-trimester bleeding
Tip		članek
Vol. in št.		Letnik 34, št. 9
Leto izdaje		2014
Obseg		str. 673-676
ISSN		0743-8346 - Journal of perinatology : official journal of the California Perinatal Association
Jezik		eng
Abstrakt		Objective: To investigate associations between first-trimester bleeding and perinatal outcomes. Study design: Registry-based survey of the period 2002 through 2010. Pregnancies with versus without first-trimester bleeding were compared using Student%s t- and %2-test. Multivariable logistic regression was used to control for potential confounders. Result: 9924 singleton and 275 twin pregnancies with first-trimester bleeding, and 160%099 singleton and 2710 twin pregnancies without bleeding were included. Bleeding increased the risk of preterm birth in singletons (odds ratio 1.48; 95% confidence interval 1.38%1.60). Risks were also increased for preterm premature rupture of membranes, abruption, previa, stillbirth and congenital anomalies, with a reduced risk of preeclampsia. The differences remained significant after adjustment for confounders. In twin pregnancies, bleeding was not significantly associated with prematurity (odds ratio 1.04; 95% confidence interval 0.81%1.34), nor with other outcomes. Conclusion: In singletons, but not in twins, the risk of perinatal complications is significantly increased after first-trimester bleeding.
Proste vsebinske oznake		perinatology first-trimester bleednig perinatal outcomes