Author/Editor		Poredoš, P; Videčnik, V
Title		Combination of physical training and pentoxifyllin is superior to pentoxifyllin treatment alone in patients with intermittent claudication
Type		članek
Source		In: Boccalon H, ed. Angiologie. Paris: John Libbey Eurotext,
Publication year		1988
Volume		str. 115-8
Language		eng
Abstract		The effect of combined treatment with pentoxifyllin and supervised training was compared to medical treatment alone in randomized cross-over study in patients with intermittent claudication. Thirty two patients were randomly assigned to two groups of 16 patients each, of wich group I first (8 weeks) received drug treatment only (pentoxifyllin 400 mg tid), and group II the combined treatment training + pentoxifyllin). During the second period of 8 weeks the patients were admitted to the reversed treatment. After the first period of 8 weeks the claudication distance increased by 18 m in group I (not significant in comparison to pretreatment value), and by 46 m in group II (p less th. 0.01). In the second period, both groups additionally improved their performance: group I, receiving at that time combined treatment, improved its claudication distance for 59 m (p less th. 0.05), while group II receiving only pentoxifyllin, improved for 32 m (p less th 0.05). The results showed that physical training was an important adjunct for medical treatment in patients with intermittent claudication and certainly superior to medical treatment alone.
Descriptors		INTERMITTENT CLAUDICATION PENTOXIFYLLINE PHYSICAL THERAPY TREATMENT OUTCOME