Avtor/Urednik		Lanišnik-Rižner, Tea
Naslov		Molekularni označevalci endometrioze - možnost razvoja neinvazivne diagnostike?
Prevedeni naslov		Molecular biomarkers of endometriosis a an option for non-invasive diagnostics?
Tip		članek
Vol. in št.		Letnik 83, št. 11
Leto izdaje		2014
Obseg		str. 782-791
ISSN		1581-0224 - Zdravniški vestnik
Jezik		slv
Abstrakt		Endometriosis is a common gynaecological disease defined as a presence of endometrial like tissue outside the uterine cavity. Estimates show that this disease affects up to 10% of premenopausal women and 35%-50% of women with infertility. At present minimal and mild stages of endometriosis can only be unequivocally diagnosed invasively, using laparoscopy. There is thus an urgent need for discovery of biomarkers for non-invasive diagnosis. With the introduction of 'omics' methodologies, we have witnessed immense progress in the field of biomarkers of endometriosis. This manuscript overviews different approached for discovery of biomarkers and presents the biomarkers with the highest diagnostic potential. Current status in the field of endometriosis biomarker discovery and potential for their introduction into clinics are discussed.
Proste vsebinske oznake		proteomics transcriptomics metabolomics proteomika transkriptomika metabolomika