Avtor/Urednik     Meden-Vrtovec, H
Naslov     Pure FSH (Metrodin) for ovarian stimulation in the IVF-ET programme
Tip     članek
Vir     Clin Exp Obstet Gynecol
Vol. in št.     Letnik 22, št. 1
Leto izdaje     1995
Obseg     str. 9-13
Jezik     eng
Abstrakt     Purpose: a comparative analysis of the clinical effectiveness of pure FSH (Metrodin) and convetional gonadotropin (Pergonal) for ovarian stimulation was performed. Methods: each group consisted of 30 selected patients with tubal infertility, practically identical by average age, duration of infertility, age at menarche, weight and height and husband's semen analysis. The average number of vials of drug used for stimulation, number of oocytes retrieved and embryos transferred was the same for both groups of patients. The failure of oocyte retrieval and fertilization was higher in the Pergonal (16.8 percent) than in the Metrodin group (6.8 percent). Results: in both groups there were 8 pregnancies - 4 in the Pergonal and 4 in Metrodin group. All pregnancies in the pure FSH group resulted in the delivery of a healthy baby, while in the Pergonal group there were two deliveries and two spontaneous abortions. Author's conclusions: evaluating the data we can conclude that pure FSH stimulation provides respectively lower failure and spontaneous abortion rates than Pergonal stimulation, leading to a higher take home baby rate.
Deskriptorji     OVULATION INDUCTION
INFERTILITY, FEMALE
FSH
MENOTROPINS
FERTILIZATION IN VITRO