Avtor/Urednik     Gleber-Netto, Frederico O.; Braakhuis, Boudewijn J. M.; Triantafyllou, Asterios; Takes, Robert P.; Kelner, Natalie; Rodrigo, Juan P.; Strojan, Primož; Vander Poorten, Vincent; Rapidis, Alexander D.; Rinaldo, Alessandra; Brakenhoff, Ruud H.; Ferlito, Alfio; Kowalski, Luiz P.
Naslov     Molecular events in relapsed oral squamous cell carcinoma
Tip     članek
Vol. in št.     Letnik 51, št. 8
Leto izdaje     2015
Obseg     str. 738-744
ISSN     1368-8375 - Oral oncology
Jezik     eng
Abstrakt     Relapses have a great impact on both the morbidity and mortality rates of oral squamous cell carcinoma (OSCC) patients. Current classification criteria are imprecise and need improvements. Recent advances in understanding of OSCC relapses on a molecular level provide new possibilities to better classify true recurrences and second primary tumors. This review discusses the limitations of the current OSCC relapse classification method and presents possible alternatives to improve this classification based on molecular techniques. Moreover, these molecular techniques add to the further understanding of these lesions and may provide tools for clinical management.
Proste vsebinske oznake     rak grla
molekuladna diagnoze
ploščatocelični rak
oral cancer
molecular diagnosis
squamous cell carcinoma