Avtor/Urednik     Al-Sabti, K
Naslov     Micronuclei induced by selenium, mercury, methylmercury and their mixtures in binucleated blocked fish erythrocyte cells
Tip     članek
Vir     Mutat Res
Vol. in št.     Letnik 320, št. 1-2
Leto izdaje     1994
Obseg     str. 157-63
Jezik     eng
Abstrakt     The genotoxic effects of low concentrations of Se(IV), Hg2+, and CH3HgCl added separately or together (Se(IV)/CH3HgCI) were studied by determining the induction of micronuclei in the binucleated erythrocytes of Prussian carp. The frequencies of micronuclei were elevated in a dose-dependent manner in all treatments when compared to the relevant controls. Addition of Se(IV) reduced the frequencies of micronuclei in treatments with both forms of mercury. This novel approach to genotoxicity testing using binucleated cytokinesis-blocked erythrocytes in fish appears to be worth further study as a method for monitoring the genotoxicity of waterborne pollutants.
Deskriptorji     CARP
MERCURY
MICRONUCLEUS TESTS
MUTAGENS
SELENIUM
CELL DIVISION
CYTOCHALASIN B
ENVIRONMENTAL MONITORING
ERYTHROCYTES
METHYLMERCURY COMPOUNDS
WATER POLLUTANTS