Avtor/Urednik		Pavičić, J; Škreblin, M; Kregar, I; Tušek-Žnidarič, M; Stegnar, P
Naslov		Embryo-larval tolerance of Mytilus galloprovincialis, exposed to the elevated sea water metal concentrations-I. Toxic effects of Cd, Zn and Hg in relation to the metallothionein level
Tip		članek
Vir		Comp Biochem Physiol
Vol. in št.		Letnik 107, št. 2
Leto izdaje		1994
Obseg		str. 249-57
Jezik		eng
Abstrakt		Developing eggs of Mytilus galloprovincialis were exposed to elevated concentrations of sea water cadmium, zinc and mercury, 48 hr postfertilization, in order to study the toxic effects at the morphological and biochemical level comparatively. Decreasing order of metal toxicity (Hg higher than Zn higher than Cd) was based on the proportion of normally formed straight-hinge veliger larvae and upon the growth inhibition of the primary larval shell. Metal-induced proteins isolated from homogenate extract of the metallothionein class due to their high metal content as well as according to their chromatographic and spectral properties. The inverse relationship between relative toxicity level amounts of total and induced metal bound to MT has been found to be described by the function of a potency type. Combined exposure to zinc and cadmium simultaneously, resulted in an antagonistic effect, showing a larger proportion of normally formed veliger larvae and smaller growth inhibition in comparison with the sum of single metal effects. The induction of MT in larvae subjected to cadmium and zinc mixture was markedly larger than the addition of individual metal effects.
Deskriptorji		MUSSELS LARVA ZINC CADMIUM MERCURY METALLOTHIONEIN SEAWATER WATER POLLUTION, CHEMICAL TIME FACTORS CHROMATOGRAPHY, GEL SPECTROPHOTOMETRY, ATOMIC ABSORBTION NEUTRON ACTIVATION ANALYSIS