Avtor/Urednik | Rutar, Veronika; Girelli, Luisa; Zupanc, Vlasta; Belič, Aleš; Manouilidou, Christina; Koritnik, Blaž; Bon, Jurij; Pečarič-Meglič, Nuška; Vrabec, Matej; Žibert, Janez; Repovš, Grega; Zidar, Janez | |
Naslov | Beyond aphasia | |
Tip | članek | |
Vol. in št. | , št. Vol. 163 | |
Leto izdaje | 2016 | |
Obseg | str. 10-21 | |
ISSN | 0093-934X - Brain and language | |
Jezik | eng | |
Abstrakt | Broca¼s region and adjacent cortex presumably take part in working memory (WM) processes. Electrophysiologically, these processes are reflected in synchronized oscillations. We present the first study exploring the effects of a stroke causing Broca¼s aphasia on these processes and specifically on syn- chronized functional WM networks. We used high-density EEG and coherence analysis to map WM net- works in ten Broca¼s patients and ten healthy controls during verbal WM task. Our results demonstrate that a stroke resulting in Broca¼s aphasia also alters two distinct WM networks. These theta and gamma functional networks likely reflect the executive and the phonological processes, respectively. The striking imbalance between task-related theta synchronization and desynchronization in Broca%s patients might represent a disrupted balance between task-positive and WM-irrelevant functional networks. There is complete disintegration of left fronto-centroparietal gamma network in Broca¼s patients, which could reflect the damaged phonological loop. | |
Proste vsebinske oznake | Broca¼s aphasia EEG coherence Working memory Phonological loop Multiple demand network Default mode network Synchronized oscillations Theta Gamma |