Author/Editor		Amnon, Ariel; Fležar, Matjaž
Title		Inhaled therapies in patients with moderate COPD in clinical practice
Type		članek
Vol. and No.		, št. Vol. 13
Publication year		2018
Volume		str. 45-56
ISSN		1178-2005 - International journal of chronic obstructive pulmonary disease
Language		eng
Abstract		COPD is a complex, heterogeneous condition. Even in the early clinical stages, COPD carries a significant burden, with breathlessness frequently leading to a reduction in exercise capacity and changes that correlate with long-term patient outcomes and mortality. Implementation of an effective management strategy is required to reduce symptoms, preserve lung function, quality of life, and exercise capacity, and prevent exacerbations. However, current clinical practice frequently differs from published guidelines on the management of COPD. This review focuses on the current scientific evidence and expert opinion on the management of moderate COPD: the symptoms arising from moderate airflow obstruction and the burden these symptoms impose, how physical activity can improve disease outcomes, the benefits of dual bronchodilation in COPD, and the limited evidence for the benefits of inhaled corticosteroids in this disease. We emphasize the importance of maximizing bronchodilation in COPD with inhaled dual-bronchodilator treatment, enhancing patient-related outcomes, and enabling the withdrawal of inhaled corticosteroids in COPD in well-defined patient groups.
Keywords		kronična obstruktivna pljučna bolezen pljučne bolezni diagnostika kajenje spirometrija