Author/Editor     Kulbacka, Julita; Paczuska, Joanna; Rembiałkowska, Nina; Saczko, Jolanta; Kiełbowicz, Zdisław; Kinda, Wojciech; Liszka, Bartłomiej; Kotulska, Małgorzata; Kos, Bor; Miklavčič, Damijan; Tozon, Nataša; Čemažar, Maja
Title     Electrochemotherapy combined with standard and CO[sub]2 laser surgeries in canine oral melanoma
Type     članek
Vol. and No.     Letnik 54, št. 4
Publication year     2017
Volume     str. 181-186
ISSN     1580-4003 - Slovenski veterinarski zbornik = Slovenian veterinary research
Language     eng
Abstract     Oral melanomas commonly occur in elderly dogs resulting in darkly pigmented areas of the mouth, tongue and gums. The main object of this study was a severe melanoma diagnosed in the jaw of a 15-year-old dog and its palliative treatment with electrochemotherapy. The tumour spread throughout the jaw including bones. Electrochemotherapy (ECT) with bleomycin and calcium solution (CaCl2) was combined with standard and CO2 laser surgeries. The treatment resulted in good local control of the tumour mass after one ECT session with bleomycin and a second ECT session with calcium ions solution. ECT significantly reduced bleeding and enhanced success of the surgery. The combination of ECT with surgical debulking resulted in rapid recovery and regaining of physiological activities, including normal feeding by the dog.This case demonstrates that the protocol combining ECT and surgery is promising in palliative melanoma treatment.
Keywords     melanom ust
oralni melanom
elektrokemoterapija
eksperimentalna onkologija
psi
melanom v ustni votlini
CO2
laser
bleomicin
kalcijevi ioni
oral melanoma
electrochemotherapy
eksperimental oncology
canine melanoma
CO2
laser
bleomycin
calcium ions