Author/Editor		Tomašič, Tihomir; Jakopin, Žiga; Anderluh, Marko
Title		Protivirusne učinkovine proti SARS-CoV-2 za zdravljenje bolezni covid-19
Translated title		Antiviral drugs against SARS-CoV-2 for the treatment of covid-19
Type		članek
Vol. and No.		Letnik 71, št. 2
Publication year		2020
Volume		str. 133-140
ISSN		0014-8229 - Farmacevtski vestnik : strokovno glasilo slovenske farmacije
Language		slv
Abstract		Bolezen covid-19, ki jo povzroča novi koronavirus, je lahko tudi smrtna, zato je razvoj novih protivirusnih učinkovin z delovanjem proti SARS-CoV-2 izrednega pomena. V preglednem članku bomo predstavili makromolekulska prijemališča virusa SARSCoV-2 kot potencialne tarče za razvoj zdravilnih učinkovin ter učinkovine ali kandidate za učinkovine, ki delujejo protivirusno in kažejo obetavne učinke v terapiji covid-19.The covid-19 disease, which is caused by SARSCoV-2, can be fatal. Therefore, there is an urgent need for the development of novel antiviral drugs against SARS-CoV-2. In this review article, we describe macromolecular structures of SARS-CoV-2 as potential targets for antiviral drugs. Furthermore, we present drugs or drug candidates with antiviral mode of action and promising effects in covid-19 therapy.
Descriptors		Pandemije Virusne infekcije
Keywords		covid-19 koronavirus protivirusne učinkovine SARS-CoV-2