Author/Editor		Patrinos, George P.; Andritsou, Asimina; Chalikiopoulou, Konstantina; Mendrinou, Effrosyni; Tsermpini, Evangelia Erini
Title		Pharmacogenomics in clinical care
Type		članek
Source		In: Applied genomics and public health London, United Kingdom San Diego, CA : Elsevier/Academic Press
Publication year		2020
Volume		str. 111-130
Language		eng
Abstract		Pharmacogenomics refers to the genetic basis of the interindividual differences in drug response, in terms of efficacy and toxicity. Pharmacogenomics aims to redefine disease management and patient stratification, with direct impact not only on the quality of life of the patients but also on the reduction of the overall cost of health-care expenditure. The latter has important implications in modern clinical practice as well as public health. This chapter aims to summarize our current knowledge pertaining to the applications of pharmacogenomics in clinical care, in particular the most important medical specialties, namely, cardiology, oncology, and psychiatry, and also addresses important aspects of pharmacogenomics in relation to public health.
Keywords		farmakogenomika neželeni učinki zdravila javno zdravje pharmacogenomics adverse drug reactions public health