| Author/Editor | Franić, Damir; Fistonić, Ivan; Franic Ivanisevic, Maja; Perdija, Željko; Križmarić, Miljenko | |
| Title | Pixel CO2 laser for the treatment of stress urinary incontinence | |
| Type | članek | |
| Vol. and No. | Letnik 53, št. 4 | |
| Publication year | 2021 | |
| Volume | str. 514-520 | |
| ISSN | 1096-9101 - Lasers in surgery and medicine | |
| Language | eng | |
| Abstract | Background and Objectives: Energy-based treatments have been found to be a promising treatment modality for improving stress urinary incontinence (SUI) symptoms. This prospective two-center study was designed to evaluate the efficacy of fractiona-pixel CO2 laser for the treatment of SUI. Study Design/Materials and Methods: Eighty-five women with SUI symptoms as per the cough stress test and validated International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI-SF), were treated intravaginally with Pixel-CO2 laser. Two treatment sessions were performed with a 1-month interval. Safety and treatment tolerance were assessed by the visual analog scale (VAS) immediately and at 1 week after each laser treatment. Associations of age and body mass index (BMI) with the ICIQ-UI-SF score were statistically assessed by the Jonckheere-Terpstra test. Results: The ICIQ-UI-SF score was 12.0 at baseline, 7.0, after the first treatment, and 3.5 after the second treatment (P = 0.001). For women with BMI (25.0-29.9), the ICIQ-UI-SF score was 9.0 at the baseline, 6.0 after 1 month, and 5.0 at the 6 months follow-up visit (P = 0.04). For women with BMI % 30.0, the ICIQ-UI-SF score was reduced from 14.0 to 8.0 1 month after the baseline and 5.0 at the 6-month follow-up visit (P = 0.001). SUI severity evaluation at baseline showed that 27.1% of women had mild, 24.7% had moderate, 45.9% had severe, and 2.4% had very severe SUI symptoms. SUI severity scores were significantly reduced, with 45.8% of women with no SUI symptoms, 18.8% with mild, 20.8% with moderate, and 14.6% with severe SUI symptoms at the 6-month follow-up. The patient's evaluation of VAS after the first treatment was 1.0-1.5 (0%10) and 0.0 1 week after the second treatment. Conclusion: Fractional-pixel CO2 laser is safe and effective for treating SUI. No adverse event or significant pain was reported during or after the procedure. Its safety and efficacy are clearly demonstrated. | |
| Keywords | stress urinary incontinence pixel CO2 laser stresna inkotinenca zdravljenje z laserjem CO2 laser točkovni laserji |