Author/Editor		Dernovšek, Mojca Zvezdana
Title		Prevalenca diskinezij pri ambulantnih bolnikih na vzdrževalnem nevroleptičnem zdravljenju (pilotska raziskava)
Translated title		The prevalence of dyskinesia in outpatients on maintenance regimen of depot neuroleptics (pilot study)
Type		članek
Source		Zdrav Vars
Vol. and No.		Letnik 35, št. 1-2
Publication year		1996
Volume		str. 17-8
Language		slo
Abstract		Using Abnormal Involuntary Movement Scale (AIMS), the prevalence of tardive dyskinesia (TD) was assessed in a sample of 50 psychiatric outpatients (25 males and 25 females) with long term depot neuroleptics maintenance therapy. Demographic, clinical and drug history data were collected. The total duration of illness was longer for males compared to females. The duration of neuroleptic treatment was the same as the duration of illness. Males were taking significantly higher doses of neuroleptics compared to females. Dyskinetic involuntary movements were found in 66 percent of patients (20 males and 13 females). Probable TD was found in 12 percent of patients (4 males and 2 females), but none of them noticed it or complained about it.
Summary		Nevroleptiki se uporabljajo za zdravljenje psihoz. Nastanek tardivnih diskinezij (TD) je povezan z daljšo izpostavljenostjo nevroleptikom. Namen raziskave je bil ugotoviti prevalenco diskinezij pri naključno izbranih 50 ambulantnih bolnikih s psihozo (25 moških in 25 žensk), ki so na vzdrževalnem depojskem nevroleptičnem zdravljenju s pregledom in uporabo lestvice AIMS za oceno zgibkov. Avtorica je zbrala tudi nekatere demografske, klinične in farmakološke podatke. Celotna prevalenca zgibkov je bila 66% (20 moških in 13 žensk), od tega je le 6 bolnikov (12%) (4 moški in 2 ženski) izpolnjevalo merila za diagnozo TD. Moški so zaradi daljšega trajanja bolezni nevroleptike prejemali dlje časa, prejemali pa so jih tudi v višjem odmerku, zato je pri njih prevalenca zgibkov večja. Zgibke bolniki niso opazili in jih niso motili.
Descriptors		ANTIPSYCHOTIC AGENTS DYSKINESIA, DRUG-INDUCED