Author/Editor		Van Geloven, Nan; Giardiello, Daniele; Bonneville, Edouard F; Teece, Lucy; Ramspek, Chava L; Van Smeden, Maarten; Snell, Kym I E; Van Calster, Ben; Pohar Perme, Maja
Title		Validation of prediction models in the presence of competing risks
Type		članek
Vol. and No.		, št. Vol. 377
Publication year		2022
Volume		str. 1-7
ISSN		1756-1833 - British medical journal (Clinical research ed.) (Online)
Language		eng
Abstract		Thorough validation is pivotal for any prediction model before it can be advocated for use in medical practice. For time-to-event outcomes such as breast cancer recurrence, death from other causes is a competing risk. Model performance measures must account for such competing events. In this article, we present a comprehensive yet accessible overview of performance measures for this competing event setting, including the calculation and interpretation of statistical measures for calibration, discrimination, overall prediction error, and clinical usefulness by decision curve analysis. All methods are illustrated for patients with breast cancer, with publicly available data and R code.
Keywords		statistics medicine validation of prediction models statistika medicina validacija napovednih modelov