Author/Editor		Pečovnik-Balon, B
Title		The effect of peroral calcitriol in small doses on mild secondary hyperparathyroidism in patients on hemodialysis
Type		članek
Source		Am J Nephrol
Vol. and No.		Letnik 15, št. 5
Publication year		1995
Volume		str. 401-6
Language		eng
Abstract		Our prospective 1-year study comprises 93 patients of both sexes, various ages and various dialysis duration. Among them, 31 patients with a concentration of Ca in blood under 2.7 mmol/l, a concentration of P under 1.8 mmol/l and a concentration of PTHi over 65 pg/ml (group 0) received calcitriol 0.25 microgramx418p4The control group consisted of patients not receiving calcitriol and having normal Ca and P metabolism (group 1). The rest of the patients had a concentration of P over 1.8 mmol/l and could not be given calcitriol. A comparison of the dynamics of average plasmic concentrations of Ca, P, AP, PTHi and X-ray changes in group 0 and 1 at the beginning of the investigation and 1 year later was carried out. At the termination of the 1-year treatment, when compared to the initial state, a statistically significant increase in the concentration of Ca (p less th. 0.005) and in the concentration of P (p less th. 0.005) was noted in group 0. The average concentration of PTHi decreased to the desired level, the X-ray changes characteristic of secondary hyperparathyroidism progressed more slowly in group 0.
Descriptors		CALCITRIOL HEMODIALYSIS HYPERPARATHYROIDISM ADMINISTRATION, ORAL ADULT AGED ALKALINE PHOSPHATASE CALCITRIOL CALCIUM HYPERPARATHYROIDISM MIDDLE AGE PARATHYROID HORMONES PHOSPHATES PROSPECTIVE STUDIES