Author/Editor		Košnik, Mitja; Mušič, Ema; Šuškovič, Stanislav; Šilar, M
Title		Alergija za sršenji strup
Translated title		Hornet venom allergy
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 65, št. Suppl 2
Publication year		1996
Volume		str. II-3-4
Language		slo
Abstract		Background. We wanted to establish whe hornet venom is appropriate for treatment of patients with allergic reaction to hornet stings. Methods. In order to identify which venom induced sensitization, we performed inhibition tests in 21 patients who experienced anaphylactic reaction after wasp or hornet sting and determined the insect responsible. Results. All patients with allergic reaction following hornet sting were sensitized either to wasp venom or to completely crossreactive epitopes only. Conclusions. A vast majority of patients with anaphylactic raction after hornet sting are sensitized with wasp venom. We think that wasp venom is an appropriate immunotherapeutic agent for those patients except for the patients in whon primary sensitisation to hornet venom is proved by inhitibion tests.
Summary		Izhodišča. Ugotiviti, kateri strup je mogoče ustrezno uporabiti za imunoterapijo bolnikov, ki so imeli sistemsko alergijsko reakcijo po piku sršena. Metode. Enaindvajsetim bolnikom, ki so imeli anafilaktično reakcijo po piku sršena oziroma ose in so prepoznali žuželko, smo z absorpcijskim testom ugotovili, kateri od obeh strupov je povzročil alergijsko senzibilizacijo. Rezultati. Vsi bolniki, ki so imeli alergijsko reakcijo po piku sršena, so bili senzibilizirani za osji strup ali pa le za antigenske determinante, ki so skupne osjemu in srŠenovemu strupu. Zaključek. Velika večina bolnikov, ki imajo alergijsko reakcijo po piku sršena, je primarno senzibilizirana s strupom os. Zato menimo, da je osji strup ustrezen za imunoterapijo teh bolnikov. Le bolnike, katerim z obsorpcijskimi testi ugotovimo primarno senzibilizacijo s strupom sršena, smemo zdravili s strupom sršena.
Descriptors		INSECT BITES AND STINGS WASP VENOMS ANAPHYLAXIS DESENSITIZATION, IMMUNOLOGIC IGE WASPS