Author/Editor		Poljak, M; Žener, N; Seme, K; Kristančič, L
Title		Particle agglutination test "serodia HIV-1/2" as a novel anti-HIV-1/2 screening test: comparative study on 3311 serum samples
Type		članek
Source		Folia Biol (Praha)
Vol. and No.		Letnik 43
Publication year		1997
Volume		str. 171-3
Language		eng
Abstract		Enzyme immunoassays are most widley used screening tests for antibodies to human immunodeficiency viruses (HIV). Nevertheless, the need of simpler, noninstrumented tests is evident in many parts of the world, where laboratory facilities and trained personnel are limited, and HIV incidence is high. A recently developed variant of gelatin-particle agglutination tests, Serodia HIV-1/2 (Fujirebio Inc., Tokyo, Japan), is one of such simple and noninstrumented tests. To evaluate its utility, 3311 serum samples (281 anti-HIV-1 positive, 8 anti-HIV-2 positive and 3022 anti-HIV-1/2 negative) obtained from 2632 individuals from Slovenia, other parts of former Yugoslavia and Senegal were investigated. No false-negative results and only one false-positive result were obtained during the procedures, giving overall sensitivity and specificity of the particle agglutination test of 100% and 99.97%, respectively. We have concluded that Serodia HIV-1/2 antibodies, suitable for small blood banks and for epidemiological surveys.
Descriptors		HIV INFECTIONS HIV SEROPOSITIVITY AIDS SERODIAGNOSIS AGGLUTINATION TESTS