Author/Editor		Pogačnik, Ana; Zidar, Nina
Title		Malignant rhabdoid tumor of the liver diagnosed by fine needle aspiration cytology: a case report
Type		članek
Source		Acta Cytol
Vol. and No.		Letnik 41, št. 2
Publication year		1997
Volume		str. 539-43
Language		eng
Abstract		BACKGROUND: Primary malignant rhabdoid tumor (MRT) of the liver is a rare tumor of early infancy, with a grim prognosis. CASE: A 17-month-old female presented with a palpable mass in the upper right side of the abdomen. Ultrasonographically guided fine needle aspiration biopsy of the tumor contained malignant cells with medium-sized, vesicular nuclei; prominent nucleoli; and well-defined cytoplasm exhibiting paranuclear, dense inclusions. These inclusions reacted positively with cytokeratin and vimentin. Ultrastructural examination showed the presence of intermediate cytoplasmic filaments. CONCLUSION: Cytomorphologic and immunocytochemical characteristics permit the preoperative differentiation of MRT from other malignant tumors of childhood. That facilitates treatment planning and precludes unnecessary surgical intervention.
Descriptors		LIVER NEOPLASMS RHABDOID TUMOR BIOPSY, NEEDLE CELL NUCLEOLUS FATAL OUTCOME INCLUSION BODIES INFANT KERATIN LUNG NEOPLASMS MICROSCOPY, ELECTRON PROGNOSIS VIMENTIN