Author/Editor		Komadina, Radko
Title		Merske značilnosti stereoloških metod za diagnosticiranje osteoporoze
Translated title		The comparison of histomorphometric methods for diagnosing osteoporosis
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 36, št. 2
Publication year		1997
Volume		str. 213-20
Language		slo
Abstract		The histomorphometric analysis represents invasive diagnostic method for osteoporosis and other metabolic bone diseases. The manual, semiautomatic and automatic histomorphometric method were compared by analysing the undecalcified bone samples. Validity of the maual method was 0.94, validity of the semiautomatic method was 0.91, validity of the automatic method was 0.67. Reliability of the semiautomatic method according to manual method as refference was 0.85, of the automatic method 0.99. The best resuft of accuracy was found in manual method, but was not statistically significant. In efficiency there were no statistically significant differences. The manual method proved with results of validity, reliabilrly aocvracy and efficiency seems to be the superior to semiautomatic and automatic histomorphometric method for bone samples.
Summary		Stereološka analiza kostnine je invazivna diagnostična metoda za odkrivanje in spremljanje osteoporoze in drugih presnovnih bolezni kosti. Na preparatih kostnih rezin, ki niso bile dekalcinirane, so primerjali ročno, polavtomatsko in avtomatsko stereološko metodo. Z anesljivost ročne metode je bila 0,94, polavtomatske 0,91 in avtomatske 0,67. Glede na ročno motodo je bila veljavnost polavtomatske 0,85, avtomatske pa 0,99. Največjo natančnost je imela ročna metoda, vendar brez statistično značilnih razlik. Po gospodarnosti, ki je prikazana z indeksom ekonomičnosti, niso našli razlik med vsemi tremi metodami. Za histološko analizo kostnine je ročna metoda še vedno najprimernejša.
Descriptors		OSTEOPOROSIS HISTOLOGICAL TECHNIQUES