Avtor/Urednik     Soomets, Ursel; Haellbrink, Mattias; Zorko, Matjaž; Langel, Uelo
Naslov     From galanin and mastoparan to galparan and transportan
Tip     članek
Vir     Current Topics in Peptide & Protein Research
Vol. in št.     Letnik 2
Leto izdaje     1997
Obseg     str. 83-113
Jezik     eng
Abstrakt     Galparan and transportan are two galanin/mastoparan chimeras that display drastically different properties from the parent peptides. In contrast to mastoparan, galparan e.g. inhibits heterotrimeric G-proteins and has a biphasic effect on the Na+/K+-ATPase. Transportan is a cell penetrating peptide, potentially capable of high efficiency transport of large hydrophilic compounds, such as peptides and oligonucleotides, over the plasma membrane. In this article we review the actions of galparan and transportan as well as the literature on their parent peptides, galanin and mastoparan.
Deskriptorji     GALANIN
CHIMERIC PROTEINS
WASP VENOMS
BIOLOGICAL TRANSPORT, ACTIVE
STRUCTURE-ACTIVITY RELATIONSHIP