Author/Editor		Sočan, M; Marinič-Fišer, N; Kotnik, A
Title		Primerjava testa reakcije vezave komplementa z indirektno ELISA za virus influence A, B, respiratorni sincicijski virus in adenovirus pri bolnikih z doma pridobljeno pljučnico
Type		članek
Source		In: Bole-Hribovšek V, Ocepek M, Klun N, editors. Zbornik s programom 2. kongres slovenskih mikrobiologov z mednarodno udeležbo; 1998 sep 27-30; Portorož. Ljubljana: Slovensko mikrobiološko društvo,
Publication year		1998
Volume		str. 404-7
Language		slo
Abstract		Respiratory syncycial virus, virus influenza A and B, and adenovirus are a common cause of respiratory tract infections. The acute infection can be demonstrated by different direct and indirect methods. In patients hospitalized with CAP, the viral isolation and antigen detection from the throat swabs for all above mentioned viruses was performed. In the paired serum samples complement fixation test and indirect ELISA (Virion-Serion, Germany) were done for RSV, virus influenza A and B, and adenovirus. In 152 patients, there was no virus isolated, four had influenza A antigen positive, in three RSV and one influenza B antigen was found. The sensitivity of influenza A IgA and IgG antibodies (comparing to CF) was 70,8% and 62,5%, the specificity 93,7% and 96,1%, respectively. The specificity of influenza B IgA, IgG antibodies specific IgA antibodies reached only 72,7%. Low sensitivity was also detected for RSV and adenoviral IgA antibodies (14,2% and 40%, respectively). The correlation between CF and ELISA was slightly better for specific IgG antibodies.
Descriptors		PNEUMONIA, VIRAL INFLUENZA A VIRUS INFLUENZA B VIRUS RESPIRATORY SYNCYTIAL VIRUS, HUMAN ADENOVIRUSES, HUMAN COMPLEMENT FIXATION TESTS ENZYME-LINKED IMMUNOSORBENT ASSAY IGG IGA