Author/Editor		Takač, Iztok; Arko, Darja; Gorišek, Borut; Kodrič, Tatjana
Title		Spremljanje bolnic po konizaciji materničnega vratu z diatermijsko zanko
Translated title		Follow-up of the patients after loop diathermy conization of the uterine cervix
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 66, št. 11
Publication year		1997
Volume		str. 571-3
Language		slo
Abstract		Background. Our purpose was to study the results of a follow-up of patients after loop diathermy conization of the uterine cervix. Methods. Eighty-eigh patients treated with loop diathermy conization were recruited from the Colposcopy clinic of Maribor Teaching Hospital between 1993 and 1995. Histologic specimens were evaluated for endocervical glandular and margin involvement. Patients were scheduled for follow-up colposcopy and cervical cytology 3 months after their initial loop procedure. Those found to be disease-free were followed up with intensive colposcopic and cytologic surveillance. The others were treated adequately. Results. In 73 (83.0%) cones, the margins were free of disease. The margins exhibited neoplasia in 15 (17.0%) cases. The endocervical margins were involved in 10(11.4%) and exocervical margins in 5(5.6%) patients. In all patients with involved exocervical margins, the cervical smear obtained 3 months after the operation was negative. Among the patients with involved endocervical margins, 5(50.0%) had a negative cervical smear obtained 3 months after the operation. In 2(20.0%) patients the control smear was suspicious. In this subgroup two reconizations were performed. In the reconization specimens, one CIN 2 and on CIN 3 was found. Among the remaining endocervical involvement group, radical hysterectomy was performed in one (10.0%) and a simple hysterectomy in two (20.0%) patients, without waiting for the 3-months follow-up investigation. No pisitive cervical smear was found in any patient 3 months after primary conization. Conclusions. The results of cytologic and colposcopic examinations confirm the applicability and efficacy of loop diathermy conization in patients with CIN of the uterine cervix. The control cytologic report was negative in the majoority of patients with CIN in margins of the operative specimens.
Summary		Izhodišča. Namen raziskave je bil ugotoviti rezultate spremljanja bolnic po konizaciji mateničnega vratu z diatermijsko zanko. Metode. Med leti 1993 in 1995 smo pri bolnicah, poslanih iz Ambulante za kolposkopijo Splošne bolnišnice Maribor, opravili 88 konizacij z diatermijsko zanko. S histološko preiskavo smo ugotavljali stanje robov operativnih preparatov. Tri mesece po operaciji smo bolnice pregledali kolposkopijo in jim odvzeli bris materničnega vratu. Bolnice brez znakov bolezni smo nadalje spremljali kolposkopsko in citološko, ostale pa smo ustrezno zdravili. Rezultati. Robovi 73(83.0%) konusov so bili prosti. V 15 (17.0%) primerih so robovi vsebovali neoplazijo. Endocervikalni robovi so bili zajeti z neoplazijo v 10(11.4%), eksocervikalni pa v 5(5.6%) primerih. Citološki bris, odvzet 3 mesece po operaciji, je bil pri vseh bolnicah, katerih eksocervikalni robovi so vsebovali neoplazijo, negativen. Pri bolnicah, pri katerih pa so vsebovali neoplazijo endocervikalni robovi, je bil 3 mesece po operavciji citološki bris negativen v 5(50.0%) primerih. Pri 2(20.0%) je bil bris sumljiv. V tej skupini smo koonizacijo ponovili v dveh primerih. V preparatih smo tedaj našli CIN 2 in CIN 3. Med preostalimi bolnicami z neoplazijo v endocervikalnih robovih smo opravili eno (10.0%) radikalno histerektomijo in dve (20.0%) navadni histerektomiji, ne da bi čakali na kontrolni pregled. Tri mesece po konizaciji nsmo našli pozitivnega citološkega brisa pri nobeni bolnici. Zaključki. Rezultati citoloških in kolposkopskih preiskav potrjujejo uporabnost in učinkovitost konizacije y diatermijsko zanko pri bolnicah s CIN materničnega vratu. Pri večini bolnic s CIN v robovih operativnih preparatov je bil kontrolni citološki izvid negativen.
Descriptors		ELECTROCOAGULATION CERVICAL INTRAEPITHELIAL NEOPLASIA CONIZATION CERVIX NEOPLASMS FOLLOW-UP STUDIES